Quantitation of the Peripheral Blood T Cell and T Subsets Patients.
- Author:
Ai Young LEE
;
Kyu Joong AHN
;
Jai Il YOUN
;
Yoo Shin LEE
;
Myoung Hee PARK
- Publication Type:Original Article
- Keywords:
Psoriasis;
Immunology;
T cell and T subsets;
Monoclonal antibody
- MeSH:
Allergy and Immunology;
Humans;
Lymphocytes;
Muromonab-CD3;
Psoriasis
- From:Korean Journal of Dermatology
1985;23(3):283-289
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The study was performed to measure and compare the peripheral blood T cell and T subsets in normal controls and psoriatic patients. Thirty-two normal controls and fift:en psoriatic patients were subjected to the study and the percentages and the rati vs of peripheral blood T cell and T subsets were measured. The results were as follows: 1. Mean percentages of peripheral blood lymphocytes reactive with OKT3 monoclonal antibody in psoriatic patients were 72. 8+-8. 2%, They decreased significantl) as compared with these in control group(76, 6- i-4. 7%). Mc an percentages of peripheral blood lymphocytes reactive with OKT4 monoclonal antibody in psoriatic patients were 47. 3+6, 7p;. They increased as compared with these in control group(46. 5+-3. 9p;), but the increase was insignificant. 3. Mean percentages of peripheral blood lymphocytes reactive with OKT8 monoclonal antibody in psoriatic patients were 27. 2+5. 5g, They decreased significantly as compared with these in control group(30, 6- l-4. 3%) 4. Mean ratios of lymphocytes reactive with OKT4 monoclonal antibody to these reactive with OKT8 monoclonal antibody in psoriatic patients were 1.8+- 0. 48 They increased significantly as compared with these in control group(1. 6+ 0.34).
