Comparison between Power Doppler Ultrasonography and Nailfold Capillaroscopy for the Differentiation of Raynaud's Phenomenon.
- Author:
Sang Il LEE
1
;
Sang Young LEE
;
Wan Hee YOO
Author Information
1. Department of Internal Medicine, Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea. goldgu@chonbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Raynaud's phenomenon;
Doppler ultrasonography;
Capillaroscopy
- MeSH:
Classification;
Fingers;
Humans;
Microscopic Angioscopy*;
Sclerosis;
Ultrasonography, Doppler*
- From:The Journal of the Korean Rheumatism Association
2005;12(3):197-205
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To evaluate the usefulness of power Doppler ultrasonography (PDU) in diagnosing Raynaud's phenomenon (RP) and in differentiating primary RP from secondary RP comparing with nailfold capillaroscopy (NFC). METHODS: Microvascularity in the nailfold and finger tip of ten healthy controls and 36 patients with primary RP (n=16) or secondary RP (systemic sclerosis, n=20) was evaluated using PDU before and after cold challenge, respectively. Also, NFC was performed in all persons. The results of PDU were compared with the findings of NFC. RESULTS: According to the change of microvascularities before and after cold challenge, the findings of PDU are classified into 3 patterns such as normal, primary RP, and secondary RP. PDU yielded a correct classification in 87.5% of the persons analyzed (normal=100%, primary RP=87.5%, secondary RP=75%) and confirmed presence of RP in all patients with clinically diagnosed RP. There was good correlation between PDU and NFC examination for differentiating primary RP from secondary RP (Kappa=0.611, p<0.01). CONCLUSION: The PDU technique is a useful and reliable method to diagnose RP and to discriminate between primary RP and secondary RP and the results of PDU is well correlated with those of NFC examination.