Study on the prevalence of HBV Ag and HBV markers revealed through preemployment examination in asymptomatic healthy persons.
- Author:
Joo Ja KIM
1
Author Information
1. Department of Preventive Medicine, Soon Chun Hyang University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Hepatitis B Surface Antigens;
Humans;
Liver Function Tests;
Mass Screening;
Prevalence*;
Radioimmunoassay
- From:Korean Journal of Preventive Medicine
1984;17(1):203-210
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary screening test for serum HBsAg by RPHA from 4,805 persons who were clinically well through preemployment examination for the period of one calendar year of 1983 revealed 476 (9.9%) positive individual carriers. There were no significant differences in distribution of positives of serum HBsAg by age group, profession, or province area. Among positives of serum HBsAg, 356 (74.8%) showed normal findings and 120 (25.2%) showed abnormal findings in liver function test, respectively. Radioimmunoassay was done in 169 positives of HBsAg and RIA detected 10 negative persons who were positive by RPHA revealing 5.9% of false positive rate and 94.1% of sensitivity of RPHA. In RIA profile of HBV markers, pattern I (HBsAg+, Anti-HBe+) was 46.6%, pattern II (HBsAg+, HBeAg+) was 33.3%, pattern III (HBsAg+only) was 18.3%, pattern IV (HBsAg+, HBeAg+, Anti-HBs+) was 1.3%, pattern V (HBsAg+, HBeAg+, Anti-HBe+) was 0.6%, respectively. There were no positives of HBsAg among 10 persons who were negatives of HBsAg by RIA.
