Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin.
- Author:
Jin Ok BAEK
1
;
Hye Young LEE
;
Jong Rok LEE
;
Joo Young ROH
Author Information
- Publication Type:Case Report
- Keywords: Acrokeratosis paraneoplastica; Bazex syndrome; Colon cancer; Tretinoin
- MeSH: Adenocarcinoma; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Colon; Colonic Neoplasms; Female; Histiocytoma, Benign Fibrous; Humans; Hyperpigmentation; Hypotrichosis; Keratoderma, Palmoplantar; Lymph Nodes; Middle Aged; Nails; Neoplasm Metastasis; Paraneoplastic Syndromes; Respiratory System; Skin; Skin Neoplasms; Tretinoin
- From:Annals of Dermatology 2008;20(4):216-220
- CountryRepublic of Korea
- Language:English
- Abstract: Acrokeratosis paraneoplastica, or Bazex syndrome, is one of the paraneoplastic syndromes. The characteristic skin lesions include palmoplantar keratoderma, psoriasiform skin lesions, hyperpigmentation, and nail dystrophy. The most common associated neoplasms are squamous cell carcinoma of the upper respiratory tract and other kinds of tumors with cervical lymph node metastasis. A 63-year-old woman presented with an 11 month history of hyperkeratotic lesions on the palms and soles. Ten months before she had been diagnosed with adenocarcinoma of the colon and undergone a left hemicolectomy. We report a case of acrokeratosis paraneoplastica associated with colon cancer which persisted after removal of the primary cancer, but resolved with topical tretinoin treatment.
