Serum Concentration of CA-125 during the First Trimester of Normal and Abnormal Pregnancies.
- Author:
Duck Yeong RO
;
Do Kang KIM
;
Soo Pyung KIM
;
Hee Bong MOON
;
Gyu Sub KANG
;
Jee Young HWANG
;
Bong Young SHIN
;
Byeung Woo JANG
- Publication Type:Original Article
- Keywords:
CA-125;
Early pregnancy
- MeSH:
Abortion, Missed;
Female;
Humans;
Pregnancy;
Pregnancy Trimester, First*;
Pregnancy*;
Prospective Studies
- From:Korean Journal of Obstetrics and Gynecology
1998;41(11):2776-2779
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A prospective study was initiated to compare maternal serum concentration of CA-125 during the first trimester of normal and abnormal pregnancies. Serum specimens were obtained from 87 women with a normal intrauterine pregnancy and 47 women with abnormal pregnancies which were ended in spontaneo abortion or pathologically confirmed to be missed abortion. In normal pregnancies, the mean serum CA-125 concentrations were increased significantly from amenorhea 6 weeks (139.838.7 IU/ml), and were higher statistically than the values tested in the same weeks of abnormal pregnancies. In abnormal pregnancies serum CA-125 concentations were relatively lower than those of normal pregnancies. But these differences were not statistically significant except the values tested in amenorhea 6weeks. So serum levels of CA-125 may not be proved useful in monitoring of early pregnancies outcome.
