A Case of Rectal Squamous Cell Carcinoma with Metachronous Diffuse Large B Cell Lymphoma in an HIV-Infected Patient.
- Author:
Heun CHOI
1
;
Hye Won LEE
;
Hea Won ANN
;
Jae Kyung KIM
;
Hua Pyong KANG
;
Sun Wook KIM
;
Nam Su KU
;
Sang Hoon HAN
;
June Myung KIM
;
Jun Yong CHOI
Author Information
- Publication Type:Case Report
- Keywords: HIV; AIDS-related lymphoma; Squamous cell carcinoma; Oncogenic viruses
- MeSH: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Biopsy; Carcinoma, Squamous Cell*; Drug Therapy; Follow-Up Studies; HIV; Humans; Lymphoma; Lymphoma, AIDS-Related; Lymphoma, B-Cell*; Oncogenic Viruses; Rectal Neoplasms; Rectum
- From:Infection and Chemotherapy 2014;46(4):257-260
- CountryRepublic of Korea
- Language:English
- Abstract: Diffuse large B cell lymphoma (DLBCL) is one of the most common acquired immune deficiency syndrome (AIDS)-defining malignancies among human immunodeficiency virus-infected patients, and rectal cancer has recently emerged as a prevalent non-AIDS-defining malignancy. We report a case of rectal squamous cell carcinoma that was metachronous with DLBCL in an HIV-infected patient who was receiving highly active antiretroviral therapy. The patient was diagnosed with DLBCL and showed complete remission after chemotherapy. Follow-up imaging showed increased uptake at the rectum, previously treated as lymphoma. Repeated biopsy was performed and squamous cell carcinoma of the rectum was reported. After concurrent chemoradiation therapy, curative resection was performed.