Daily Mean Temperature Affects Urolithiasis Presentation in Seoul: a Time-series Analysis.
10.3346/jkms.2016.31.5.750
- Author:
Seoyeon LEE
1
;
Min Su KIM
;
Jung Hoon KIM
;
Jong Kyou KWON
;
Byung Hoon CHI
;
Jin Wook KIM
;
In Ho CHANG
Author Information
1. Department of Urology, Seonam University College of Medicine, Myongji Hospital, Goyang, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Urolithiasis;
Temperature;
Interrupted Time Series Analysis
- MeSH:
Adult;
Age Factors;
Aged;
Databases, Factual;
Emergency Service, Hospital;
Female;
Humans;
Male;
Middle Aged;
Regression Analysis;
Republic of Korea;
Risk;
Seoul;
Sex Factors;
Temperature;
Time Factors;
Urolithiasis/diagnosis/epidemiology/*etiology
- From:Journal of Korean Medical Science
2016;31(5):750-756
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study aimed to investigate the overall cumulative exposure-response and the lag response relationships between daily temperature and urolithiasis presentation in Seoul. Using a time-series design and distributing lag nonlinear methods, we estimated the relative risk (RR) of urolithiasis presentation associated with mean daily temperature, including the cumulative RR for a 20 days period, and RR for individual daily lag through 20 days. We analyzed data from 14,518 patients of 4 hospitals emergency department who sought medical evaluation or treatment of urolithiasis from 2005-2013 in Seoul. RR was estimated according to sex and age. Associations between mean daily temperature and urolithiasis presentation were not monotonic. Furthermore, there was variation in the exposure-response curve shapes and the strength of association at different temperatures, although in most cases RRs increased for temperatures above the 13℃ reference value. The RRs for urolothiasis at 29℃ vs. 13℃ were 2.54 in all patients (95% confidence interval [CI]: 1.67-3.87), 2.59 in male (95% CI, 1.56-4.32), 2.42 in female (95% CI, 1.15-5.07), 3.83 in male less than 40 years old (95% CI, 1.78-8.26), and 2.47 in male between 40 and 60 years old (95% CI, 1.15-5.34). Consistent trends of increasing RR of urolithiasis presentation were observed within 5 days of high temperatures across all groups. Urolithiasis presentation increased with high temperature with higher daily mean temperatures, with the strongest associations estimated for lags of only a few days, in Seoul, a metropolitan city in Korea.
