Predicting Factors for Recurrence in First-time Stone Formers.
10.4111/kju.2007.48.2.176
- Author:
Sung Whan JO
1
;
Sang Cheol LEE
;
Wun Jae KIM
Author Information
1. Department of Urology, Chungbuk National University College of Medicine, Cheongju, Korea. lscuro@chungbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Urinary calculi;
Recurrence;
Phosphates;
Risk factors
- MeSH:
Calcium;
Chemistry;
Female;
Follow-Up Studies;
Humans;
Male;
Multivariate Analysis;
Phosphates;
Recurrence*;
Retrospective Studies;
Risk Factors;
Urinary Calculi
- From:Korean Journal of Urology
2007;48(2):176-182
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of the present study was to determine the risk factors for predicting the recurrence in first-time urinary stone formers. MATERIALS AND METHODS: A total of 121 patients, who presented at our hospital with first-time urinary stone episodes, between 1996 and 2005, and followed up for at least 3 years, were retrospectively evaluated. Of these, 65 patients (41 males, 24 females) recurred (R group) and 56 (38 males, 18 females) not (NR group) during the follow-up period. The blood chemistry and urinary analytes values, as well as the clinical characteristics between the NR and R groups were compared by gender. p-values less than 0.05 were used to indicate statistical significance. RESULTS: There were no differences in the clinical characteristics between the NR and R groups. A comparison of the blood chemistry showed differences in the phosphate and calcium in men and women (p=0.047 and 0.034), respectively. Greater urinary excretion of phosphates were found in the R group than in the NR group (p=0.018), but was more prominent in men (p=0.006). No significant differences were found between the two groups with regard to metabolic abnormalities. A multivariate analysis revealed that urinary phosphates excretion was the sole predictor for stone recurrence (Exp beta=8.347, p=0.033). CONCLISIONS: Our results suggested that the increased excretion of urinary phosphates was a significant risk factor for stone recurrence, which might be useful as a prognostic marker.
