Discussion on the prevention and treatment of postoperative recurrence and metastasis of non-small cell lung cancer based on the " where there is mass hardness, there must be latent yang" theory
10.3969/j.issn.1006-2157.2025.02.015
- VernacularTitle:基于“痞坚之处,必有伏阳”理论探讨非小细胞肺癌术后复发转移的防治
- Author:
Jinglei LI
1
;
Shuaihang HU
1
;
Wei HOU
1
Author Information
1. Guang anmen Hospital, China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
non-small cell lung cancer;
recurrence and metastasis;
mass hardness;
latent yang;
surgical treatment
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(2):246-252
- CountryChina
- Language:Chinese
-
Abstract:
Local recurrence and distant metastasis in patients after postoperative adjuvant therapy for non-small cell lung cancer remain clinical challenges. Traditional Chinese medicine demonstrates notable advantages in preventing and managing postoperative recurrence and metastasis in lung cancer. The traditional Chinese medicine principle of " where there is mass hardness, there must be latent yang" aligns closely with non-small cell lung cancer recurrence and metastasis after surgery. The term " mass hardness" describes the dense, rock-like pathology of the lung mass, which often causes pain during growth, and " latent yang" refers to pathological yang energy that remains unexpressed owing to the obstruction of latent evils and other factors such as latent evil qi. Even after surgical removal of the primary mass, this " latent yang" may persist, representing a residual microenvironment conducive to recurrence and metastasis. In this study, the " where there is mass hardness, there must be latent yang" theory is used to investigate the relationship between " mass hardness" and " latent yang." By strengthening the lung and vital qi, promoting blood circulation, removing stasis, detoxifying, and using anti-cancer herbs, this approach aims to modulate the immune microenvironment, reduce hypoxia, and prevent inflammation. These therapeutic strategies enrich preventive and treatment options of traditional Chinese medicine for postoperative recurrence and metastasis in lung cancer.
- Full text:2025102914153870295Discussion on the prevention and treatment of postoperative recurrence and metastasis of non-small cell lung cancer based on the _ where there is mass hardness, there must be latent yang_ theory.pdf