Investigation of an outbreak of group A human G9P ［8］ rotavirus infectious diarrhea among adults in Chongqing
10.19428/j.cnki.sjpm.2025.24687
- VernacularTitle:重庆市一起成人A组G9P［8］型轮状病毒感染性腹泻暴发疫情调查
- Author:
Yang WANG
1
;
Yuan KONG
1
;
Ning CHEN
1
;
Lundi YANG
1
;
Jiang LONG
2
;
Qin LI
2
;
Xiaoyang XU
3
;
Wei ZHENG
1
;
Hong WEI
1
;
Jie LU
1
;
Quanjie XIAO
1
;
Yingying BA
1
;
Wenxi WU
1
;
Qian XU
4
;
Ju YAN
5
Author Information
1. Nanchuan District Center for Disease Control and Prevention, Chongqing 408400, China
2. Institute for Infectious Disease Control and Prevention, Chongqing Center for Disease Control and Prevention, Chongqing 400042, China
3. The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
4. Shapingba District Center for Disease Control and Prevention, Chongqing 400000, China
5. Banan District Center for Disease Control and Prevention, Chongqing 401320, China
- Publication Type:Journal Article
- Keywords:
rotavirus;
infectious diarrhea;
correctional facility;
outbreak of epidemic
- From:
Shanghai Journal of Preventive Medicine
2025;37(8):663-668
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate and analyze an outbreak of rotavirus infectious diarrhea in a prison in Chongqing Municipality, to provide a basis for adult rotavirus surveillance and prevention, and to explore the public health problems in special settings. MethodsA retrospective survey was conducted to collect and analyze data on individual cases with diarrheal disease on-site. The clinical characteristics, as well as the temporal, spatial and geographical distribution patterns of the epidemic were described. Multi-pathogen detection tests were conducted both on diarrhea cases and environmental samples, with viral genotyping performed on positive samples. A case-control analysis was performed to identify the causes of the outbreak, and an SEIR model was adopted to predict the outbreak trend and evaluate the effectiveness of interventions. ResultsA total of 65 cases were found among the inmates, with an attack rate of 2.03%. The predominant clinical manifestations included diarrhea (89.23%), watery stool (73.85%), and dehydration (18.46%). The epidemic curve indicated a “human-to-human” transmission pattern, with an average incubation period of 5‒6 days. The attack rates among chefs in the main canteen (80.00%, 8/10) and caterers (28.33%, 17/60) were significantly higher than those of other inmates （P<0.05）. Multi-pathogen polymerase chain reaction (PCR) testing detected positive for group A rotavirus, with the viral genotyping identified as G9P [8] strain. Factors such as unprotected "bare-handed" food distribution among cases with diarrhea (OR=9.512, 95%CI: 4.261‒21.234) and close contact with diarrhea cases (OR=3.656, 95%CI: 1.719‒7.778) were the possible cause of the outbreak. The SEIR model (r0=5, α=0.3, β1=0.08, β2=0.04) was constructed using prison inmates as susceptible population, aiming at fitting the initial transmission trend of the outbreak, and the epidemic rate declined rapidly after intervention measures were implemented (rt≈0). ConclusionThis rare rotavirus infection diarrhea outbreak among adults in confined settings suggests that the construction of public health prevention and control systems in prison may be overlooked. Cross infection during meal processing and distribution in the canteens of such settings is likely to be the cause of the outbreak. Given the potential neglect of public heath system construction in special settings, it is imperative to enhance the surveillance and monitoring of rotavirus and other intestinal multi-pathogens among adults, as well as the construction of public health prevention and control systems in these special settings.
