Application of bicuspid pulmonary valve sewn by 0.1 mm expanded polytetrafluoroethylene in right ventricle outflow tract reconstruction

Jianrui MA; Tong TAN; Miao TIAN; Jiazichao TU; Wen XIE; Hailong QIU; Shuai ZHANG; Jian ZHUANG; Jimei CHEN; Jianzheng CEN; Shusheng WEN; Haiyun YUAN; Xiaobing LIU

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Application of bicuspid pulmonary valve sewn by 0.1 mm expanded polytetrafluoroethylene in right ventricle outflow tract reconstruction

VernacularTitle:基于0.1 mm膨体聚四氟乙烯缝制肺动脉双叶瓣在右室流出道重建中的应用
Author: Jianrui MA ¹ ; Tong TAN ¹ ; Miao TIAN ² ; Jiazichao TU ² ; Wen XIE ² ; Hailong QIU ² ; Shuai ZHANG ² ; Jian ZHUANG ² ; Jimei CHEN ² ; Jianzheng CEN ² ; Shusheng WEN ² ; Haiyun YUAN ² ; Xiaobing LIU ²
Author Information

1. 1. Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510800, P. R. China 2. Shantou University Medical College, Shantou, 515041, Guangdong, P. R. China
2. Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong
Publication Type:Journal Article
Keywords: Right ventricular outflow tract reconstruction; pulmonary regurgitation; polytetrafluoroethylene; valved conduit; congenital heart diseases
From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2025;32(08):1127-1132
CountryChina
Language:Chinese
Abstract: Objective To introduce a modified technique of right ventricular outflow tract (RVOT) reconstruction using a handmade bicuspid pulmonary valve crafted from expanded polytetrafluoroethylene (ePTFE) and to summarize the early single-center experience. Methods Patients with complex congenital heart diseases (CHD) who underwent RVOT reconstruction with a handmade ePTFE bicuspid pulmonary valve due to pulmonary regurgitation at Guangdong Provincial People’s Hospital from April 2021 to February 2022 were selected. Postoperative artificial valve function and right heart function indicators were evaluated. Results A total of 17 patients were included, comprising 10 males and 7 females, with a mean age of (18.18±12.14) years and a mean body weight of (40.94±19.45) kg. Sixteen patients underwent reconstruction with a handmade valved conduit, with conduit sizes ranging from 18 to 24 mm. No patients required mechanical circulatory support, and no in-hospital deaths occurred. During a mean follow-up period of 12.89 months, only one patient developed valve dysfunction, and no related complications or adverse events were observed. The degree of pulmonary regurgitation was significantly improved post-RVOT reconstruction and during follow-up compared to preoperative levels (P<0.001). Postoperative right atrial diameter, right ventricular diameter, and tricuspid regurgitation area were all significantly reduced compared to preoperative values (P<0.05). Conclusion The use of a 0.1 mm ePTFE handmade bicuspid pulmonary valve for RVOT reconstruction in complex CHD is a feasible, effective, and safe technique.