Analysis of thyroid hormone levels and prevalence of thyroid abnormalities in 1152 radiation workers
10.13491/j.issn.1004-714X.2025.04.020
- VernacularTitle:1152名放射工作人员甲状腺激素水平及甲状腺异常率分析
- Author:
Meilin CHEN
1
,
2
;
Shuangyu YANG
2
;
Yan ZHANG
2
;
Haibo HUANG
2
;
Zhi WANG
2
;
Zhenzhong LIU
3
;
Jianyu WANG
1
,
2
Author Information
1. School of Public Health, North Sichuan Medical College, Nanchong 637100, China
2. Key Laboratory of Occupational Environment and Health, Guangzhou 12 th People's Hospital, Guangzhou 510620, China.
3. School of Public Health, North Sichuan Medical College, Nanchong 637100, China.
- Publication Type:OriginalArticles
- Keywords:
Radiation worker;
Thyroid hormone;
Ionizing radiation;
Low-dose;
FT3;
FT4;
TSH
- From:
Chinese Journal of Radiological Health
2025;34(4):590-594
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of low-dose ionizing radiation on the thyroid status and hormone levels of radiation workers. Methods Radiation workers who underwent occupational health examinations at a hospital in Guangzhou from 2015 to 2022 were selected as the subjects of this study. The levels of FT3, FT4 and TSH were analyzed, and the thyroid abnormality status of radiation workers in different groups were compared. Results A total of 1152 participants were included in this study, consisting of 885 (76.82%) males and 267 (23.18%) females, with an average age of (35.26 ± 10.16) years. The prevalence of thyroid abnormalities was 9.38%, which was significantly higher in females (13.86%) than in males (8.02%) (P < 0.05). The TSH level of females [(2.15 ± 1.29) mIU/L] was higher than that of males [(1.85 ± 1.20) mIU/L], while the levels of FT3 [(5.10 ± 0.64) pmol/L] and FT4 [(15.84 ± 2.32) pmol/L] in females were lower than those in males [(5.23 ± 0.63) pmol/L and (16.61 ± 2.75) pmol/L, P < 0.05]. The FT3 of industrial workers [(5.25 ± 0.63) pmol/L] was higher than that of medical workers [(5.10 ± 0.63) pmol/L], while the TSH of industrial workers [(1.80 ± 1.12) mIU/L] was lower than that of medical workers [(2.15 ± 1.37) mIU/L]. FT4 levels decreased with increasing age and duration of occupational exposure. Multivariable logistic regression analysis revealed that sex was a significant independent predictor of thyroid abnormalities among radiation workers. Female workers were more likely to experience thyroid abnormalities (β = −0.62, P < 0.05). Conclusion Low-dose ionizing radiation may have a certain impact on the thyroid status of radiation workers, especially for female workers, which requires further attention and research.
