Evaluation of cardiac involvement in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis using echocardiography combined with electrocardiography
10.13491/j.issn.1004-714X.2025.04.011
- VernacularTitle:超声心动图联合心电图对ANCA相关血管炎患者心脏受累的评价
- Author:
Aiqing LU
1
;
Ling CHEN
2
;
Xiuyun SUN
1
;
Xin DONG
1
;
Xiaoyan LI
1
;
Yongcun SUN
1
;
Shaowen LYU
1
;
Long YU
1
;
Yong ZHANG
3
Author Information
1. Department of Ultrasound of the First People’s Hospital of Jining, Jining 272100, China.
2. Library of Jining Medical University, Jining 272100, China.
3. Shandong First Medical University (School of Preventive Medicine Sciences), Jinan 250117, China.
- Publication Type:OriginalArticles
- Keywords:
Anti-neutrophil cytoplasm;
Vasculitis;
Echocardiography;
Electrocardiography
- From:
Chinese Journal of Radiological Health
2025;34(4):534-539
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate cardiac involvement in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) using echocardiography combined with electrocardiography. Methods A retrospective analysis was performed on the detailed medical records of AAV patients treated in Jining First People’s Hospital between January 2020 and December 2024. Eighty patients were enrolled in the AAV group, and the risk of heart disease was compared between the AAV group and a control group with 80 subjects matched for age, sex, and cardiovascular disease risk factors. Results Electrocardiographic abnormalities were observed in 78.75% of patients in the AAV group, while significant electrocardiographic abnormalities only occurred in symptomatic patients in the control group. There were no differences in left atrial enlargement or interventricular septal thickening between the AAV group and the control group. The overall left ventricular systolic function in the AAV group was lower than that in the control group (8.75% vs. 0). The incidence of reduced diastolic function in the AAV group was significantly higher than that in the control group (37.5% vs. 15%). The incidence rates of tricuspid regurgitation, mitral regurgitation, aortic regurgitation, and pericardial effusion in the AAV group were significantly higher than those in the control group. Pericardial thickening, aortic stenosis, pulmonary hypertension, and rare periaortic granulomas were found in the AAV group, but not in the control group. Conclusion Echocardiography and electrocardiography are important examination methods for evaluating cardiac involvement in AAV. These methods have key roles in disease screening, diagnosis and treatment, follow-up, and prognosis judgment.
