Ventricular aneurysm formation after successful intensive hemoperfusion in chlorfenapyr poisoning: a case report
10.5847/wjem.j.1920-8642.2025.092
- Author:
Ruiqiao Zhao
1
Author Information
1. Department of Emergency Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
- Publication Type:Case Reports
- From:
World Journal of Emergency Medicine
2025;16(5):511-513
- CountryChina
- Language:English
-
Abstract:
Chlorfenapyr poisoning is associated with high mortality due to the absence of evidence-based treatment strategies or specific antidotes.[1,2] Chlorfenapyr is a novel N-substituted halogenated pyrrole pro-insecticide. The active metabolite of tralopyril (a metabolite of chlorfenapyr) can uncouple oxidative phosphorylation and impair adenosine triphosphate (ATP) production.[3] Blood purification techniques, including hemoperfusion (HP), may facilitate tralopyril clearance.[4,5] Here, we present a case of severe chlorfenapyr poisoning that was treated with intensive HP. However, during follow-up, we unexpectedly found a ventricular aneurysm in the left ventricle that was not fully explained by coronary artery lesions.
