Yangyin Yiqi Decoction combined with polyethylene glycol eye drops for the treatment of dry eye disease after cataract surgery
10.3980/j.issn.1672-5123.2025.9.25
- VernacularTitle:养阴益气汤联合聚乙二醇滴眼液治疗白内障术后干眼
- Author:
Wei XIA
1
;
Lixia ZHANG
1
;
Xiuqin CHEN
1
;
Na DING
1
Author Information
1. Department of Ophthalmology, Dongtai Hospital of Traditional Chinese Medicine, Dongtai 224200, Jiangsu Province, China
- Publication Type:Journal Article
- Keywords:
Yangyin Yiqi Decoction;
polyethylene glycol eye drops;
dry eye disease after cataract surgery;
clinical efficacy;
inflammatory factors
- From:
International Eye Science
2025;25(9):1527-1531
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the efficacy of Yangyin Yiqi Decoction combined with polyethylene glycol eye drops on dry eye disease after cataract surgery and its effect on inflammatory factors in tears.METHODS:Prospective study. A total of 104 patients(104 eyes)with dry eye disease after cataract surgery admitted to our hospital from April 2022 to March 2024 were selected and randomly divided into two groups: 52 cases(52 eyes)in the control group were treated with polyethylene glycol eye drops; 52 cases(52 eyes)in the combined group were treated with Yangyin Yiqi Decoction combined with polyethylene glycol eye drops. The dry eye symptom score, tear film stability index, tear inflammatory factor level, ocular surface disease index score(OSDI)and clinical efficacy of the two groups were compared before and after treatment.RESULTS:There were 6 cases(6 eyes)lost to follow-up, and 3 cases(3 eyes)were lost to follow-up in each group, with a loss to follow-up rate of 5.8%. The total effective rate of treatment in the combination group was significantly higher than that in the control group(94% vs 80%, P=0.037), and the Schirmer I test(SIt)and tear film break-up time(BUT)were higher than those in the control group(all P<0.05), and the dry eye symptom score, corneal fluorescein staining(FL)score, IL-1β, TNF-α, hs-CRP levels in tears and OSDI score were lower than those in the control group(all P<0.05).CONCLUSION:The combination of Yangyin Yiqi Decoction and polyethylene glycol eye drops provides an effective treatment plan for patients with dry eye disease after cataract surgery. It can effectively alleviate dry eye symptoms, reduce eye discomfort, improve tear film stability and ocular surface status, and reduce inflammatory factors in tears.
