Advances in diffuse optical technology lenses for myopia control
10.3980/j.issn.1672-5123.2025.9.16
- VernacularTitle:点扩散光学技术镜片在近视控制领域的研究进展
- Author:
Kun HE
1
;
Bingxin PAN
1
;
Suyun YANG
1
;
Zhiyang HE
1
;
Mengting ZHENG
1
;
Meiling SHU
1
;
Pengfei JIANG
1
;
Shan XU
1
;
Pengfei TIAN
1
Author Information
1. Department of Ophthalmology, Zhejiang Medical & Health Group Quzhou Hospital(Zhejiang Quhua Hospital), Quzhou 324000, Zhejiang Province, China
- Publication Type:Journal Article
- Keywords:
diffuse optical technology;
myopia control;
retinal contrast signals;
clinical research;
axial length growth
- From:
International Eye Science
2025;25(9):1476-1483
- CountryChina
- Language:Chinese
-
Abstract:
Recent years have witnessed significant advancements in myopia control research through the application of diffuse optical technology(DOT)spectacle lenses. Myopia has emerged as a global public health challenge, affecting nearly half of the world's population, with childhood and adolescent myopia rates continuing to rise. DOT lenses represent an innovative myopia control intervention based on retinal contrast signal theory. These lenses incorporate micro-light scattering dots distributed across the lens surface to reduce retinal imaging contrast and modulate the influence of visual input on axial elongation, thereby slowing myopia progression. The core mechanism operates through refractive index differences between the lens substrate(1.53)and scattering dots(1.50), which generate optical scattering effects. This design maintains clear vision through a central 5 mm optical zone while effectively reducing contrast signal intensity in the peripheral retina. Large-scale randomized controlled trials, including the CYPRESS study, have demonstrated significant myopia control efficacy in children aged 6-10 years: 12-month follow-up data revealed a 74% reduction in myopia progression and a 50% reduction in axial elongation, with sustained safety and visual quality maintained over 4-year long-term follow-up. However, several aspects of DOT technology remain contentious and require further clinical validation, including its applicability across different age groups, optimal scattering dot density configurations, combined application effects with other myopia control methods, and long-term visual adaptation during extended use. This review systematically examines the theoretical foundations, design characteristics, clinical application progress, and future development directions of DOT technology, providing scientific evidence for clinical myopia prevention and control strategy formulation.
