Advances in the application of optical coherence tomography angiography in normal tension glaucoma
10.3980/j.issn.1672-5123.2025.9.11
- VernacularTitle:光学相干断层扫描血管成像技术在正常眼压性青光眼中的应用进展
- Author:
Yangyang JIN
1
,
2
;
Lurun GU
1
,
2
;
Youchen WUDENG
1
,
2
;
Qiuyang ZHANG
1
,
2
;
Guofan CAO
1
,
2
Author Information
1. The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
2. Nanjing Medical University, Nanjing 211166, Jiangsu Province, China
- Publication Type:Journal Article
- Keywords:
optical coherence tomography angiography;
normal tension glaucoma;
pathogenesis;
vessel density;
diagnosis and monitoring
- From:
International Eye Science
2025;25(9):1448-1454
- CountryChina
- Language:Chinese
-
Abstract:
Normal tension glaucoma(NTG)is a chronic optic neuropathy characterized by progressive damage to the optic nerve and visual field defects, with its pathophysiology closely linked to genetic, immune-inflammatory and vascular factors. Optical coherence tomography angiography(OCTA)is a noninvasive imaging technique that provides real-time, quantitative assessment of retinal microvascular perfusion. In recent years, OCTA has been increasingly applied in NTG studies, demonstrating significant potential in early diagnosis, disease monitoring and management. This systematic review summarizes the latest advancements in the application of OCTA for NTG, with a focus on vascular parameters in the optic nerve head and macular regions. Its diagnostic value and monitoring management are further summarized. Moreover, the current limitations of OCTA technology and the challenges related to its clinical application are critically evaluated, while exploring its future developments. These insights aim to provide a theoretical foundation for further research on NTG-related microvascular pathology and the broader clinical application of OCTA.
