Research progress on the relationship between the photobiomodulation and amblyopia

VernacularTitle:光的生物调节与弱视关系的研究进展
Author: Shuxian HU ^{1
,

2} ; Mei LIU ^{1
,

2} ; Jingjing DONG ^{1
,

2} ; Yang YANG ^{1
,

2} ; Li LIU ^{1
,

2} ; Xuan MA ^{1
,

2} ; Liyun GUO ^{1
,

2}
Author Information

1. Affiliated Hospital of Yunnan University
2. Yunnan Eye Hospital, Kunming 650021, Yunnan Province, China
Publication Type:Journal Article
Keywords: amblyopia; photobiomodulation; visual center; dopamine; melatonin
From: International Eye Science 2025;25(9):1431-1435
CountryChina
Language:Chinese
Abstract: Amblyopia is a common visual development disorder and is the main cause of monocular vision impairment in children and adults. Photobiomodulation(PBM), a non-invasive treatment method, has gradually gained attention in the field of ophthalmology. This paper begins with the macroscopic manifestation of light on the animal model of amblyopia. Additionally, it discusses the pathological changes of the amblyopic retina and the human eye's central nervous system, as well as the influence and mechanism of PBM on the visual perception and processing system and its chemical effect on the visual system through dopamine and melatonin. It examines its mechanism of action, current clinical application status, and future development direction in order to provide new ideas and theoretical foundation for amblyopia treatment.