Influencing factors and optimization methods of pre-treatment for microbiological counting method of proprietary Chinese medicine
10.12206/j.issn.2097-2024.202403014
- VernacularTitle:中成药微生物计数法前处理的影响因素和优化方法
- Author:
Nong XIAO
1
;
Shiyi LU
1
;
Wenya TANG
1
;
Minli JU
1
;
Gangfeng XU
1
;
Minghua YANG
1
Author Information
1. Shanghai Pudong Institute for Food and Drug Control, Shanghai 201203, China.
- Publication Type:Reviews
- Keywords:
proprietary Chinese medicine;
microbial limit test;
microbial counting method;
sample pre-treatment
- From:
Journal of Pharmaceutical Practice and Service
2025;43(8):373-376
- CountryChina
- Language:Chinese
-
Abstract:
Due to the diverse composition and complex physicochemical and biological characteristics, the pre-treatment of microbiological counting method （preparation of test solution） in microbiological limit test were interfered by many factors, which ultimately affected the repeatability and accuracy of test results. Improving the accuracy of microbiological test is of practical significance to ensure the safety and effectiveness of non-sterile preparations. In this paper, the key factors and optimization methods involved in the pre-treatment of proprietary Chinese medicines were systematically analyzed and summarized.
