Epidemiological and clinical characteristics of surveillance cases in a sentinel hospital for pertussis in Jiangxi Province in 2019
10.19428/j.cnki.sjpm.2025.24552
- VernacularTitle:2019年江西省一家百日咳哨点医院监测病例的流行病学与临床特征
- Author:
Hui WU
1
;
Jie LIU
1
;
Yuqin ZHAO
1
;
Shicheng GUO
1
;
Hairong WEN
2
;
Jian LI
3
Author Information
1. Institute of Immunization Planning, Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, Jiangxi 330029, China
2. Nanchang City Center for Disease Control and Prevention, Nanchang, Jiangxi 330038, China
3. Donghu District Center for Disease Control and Prevention, Nanchang, Jiangxi 330006, China
- Publication Type:Journal Article
- Keywords:
pertussis;
surveillance;
epidemiology;
clinical characteristic;
misdiagnosis
- From:
Shanghai Journal of Preventive Medicine
2025;37(6):507-510
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the epidemiological and clinical characteristics of surveillance cases in a sentinel hospital for pertussis in Jiangxi Province in 2019, and to provide corresponding references for the prevention and control of pertussis. MethodsCase investigation of pertussis was conducted among sentinel hospital surveillance cases, collecting their basic information, epidemiological characteristics, clinical characteristics, and other information. ResultsA total of 125 pertussis surveillance cases were investigated in 2019, including 73 clinically diagnosed cases (58.40%) and 52 confirmed cases (41.60%). The age of onset was mainly concentrated in children under 5 years old (108 cases, 86.40%), with the largest number of cases in infants aged less than 1-year-old (48 cases, 38.40%). Most cases had a history of receiving pertussis vaccine before onset (110 cases, 88.00%), and the intervals between the onset date and the date of last dose of pertussis vaccine in the 1‒2 doses group were significantly shorter than that in the 3‒4 doses group (U=-5.990, P<0.001). Probable household transmission of pertussis was found in 3 cases. All cases had cough symptoms, mainly manifested as whooping cough (77 cases, 61.60%), in addition to other main clinical manifestations, such as fever (76 cases, 60.80%), vomiting (30 cases, 24.00%), conjunctival congestion (27 cases, 21.60%), and inspiratory whoop (16 cases, 12.80%). A total of 73 cases (58.40%) experienced complications, including 1 death case. All the cases had multiple medical visit experiences before this visit, with an interval of 2 (0,3) days between the onset date and the first visit date. The misdiagnosis rate at the first medical visit was 88.00% (110/125), and the misdiagnosis rate of the first visit in secondary and primary hospitals was significantly higher than that in tertiary hospitals, exhibiting a statistically significant difference (χ2=21.582, P<0.001). ConclusionThe clinical symptoms of pertussis cases are often atypical, and the first diagnosis is prone to misdiagnosis, so it’s necessary to further strengthen the early diagnosis capabilities for pertussis cases in healthcare institutions, especially in the primary healthcare institutions.
