Analysis of the therapeutic effect of dual channel injection of thrombin on reducing bleeding in low-dose CT guided lung biopsy
10.13491/j.issn.1004-714X.2025.03.009
- VernacularTitle:双通道推注血凝酶减少低剂量CT引导下肺活检出血的疗效分析
- Author:
Yougang WANG
1
;
Xueren SUN
1
;
Wei WU
1
Author Information
1. Linyi Central Hospital, Linyi 276400, China.
- Publication Type:OriginalArticles
- Keywords:
Tomography;
X-ray computed tomography;
CT guidance;
Lung biopsy;
Bleeding;
Complication
- From:
Chinese Journal of Radiological Health
2025;34(3):363-367
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of dual channel (intravenous channel and puncture needle channel) and single channel (puncture needle channel) of thrombin injection in reducing bleeding during low-dose CT-guided percutaneous lung biopsy, identify the optimal method, and develop a protocol with improved safety and efficacy while minimizing radiation exposure to patients. Methods Patients who underwent CT-guided percutaneous lung biopsy at Linyi Central Hospital between May 2024 and January 2025 were selected and divided into a dual channel group (observation group) and a single channel group (control group) according to the methods of thrombin injection. The baseline characteristics (sex, age, underlying lung disease, lesion diameter, distribution, proportion of solid lesions, enhancement degree, puncture depth and time, and benign or malignant) and the differences in CT images after lung puncture (bleeding, blood diffusion distance, and blood diffusion volume) were compared between the two groups of patients. Results There were no significant differences in baseline characteristics and bleeding incidence between the two groups of patients (P > 0.05). The diffusion distance and volume of blood in the dual channel group were significantly lower than those in the single channel group (P < 0.05). Conclusion The use of dual channel thrombin injection under low-dose CT guidance cannot reduce the incidence of bleeding in lung biopsy, but it can reduce the amount of bleeding, blood diffusion to surrounding lung tissues, and intraoperative radiation exposure to patients.
