SHI Zaixiang's Clinical Experience in Using Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤） to Treat High Fever in Sepsis
10.13288/j.11-2166/r.2025.16.004
- VernacularTitle:史载祥应用柴胡桂枝干姜汤治疗脓毒症高热经验
- Author:
Tingting ZHU
1
;
Yingying LIU
2
;
Hailan CUI
3
;
Zhiying REN
4
;
Mingjing SHAO
5
;
Yan BIAN
6
;
Liyan WANG
1
;
Zhenjie CHEN
7
;
Yuan LIU
4
;
5
Author Information
1. The Sixth Hospital of Beijing，Beijing，100007
2. Beijing Chaoyang District Hospital of Traditional Chinese Medicine
3. Beijing Changping District Hospital of Traditional Chinese Medicine
4. Beijing University of Chinese Medicine
5. China-Japan Friendship Hospital
6. Beijing Hospital of Integrated Traditional Chinese and Western Medicine
7. Dongzhimen Hospital，Beijing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
sepsis;
high fever;
Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤）;
experience of famous doctors;
SHI Zaixiang
- From:
Journal of Traditional Chinese Medicine
2025;66(16):1645-1648
- CountryChina
- Language:Chinese
-
Abstract:
This paper summarizes Professor SHI Zaixiang's clinical experience in treating high fever caused by sepsis using Chaihu Guizhi Ganjiang Decoction （柴胡桂枝干姜汤）. He holds that the key pathogenesis of sepsis involves constrained heat in the shaoyang and internal accumulation of water and fluids. The clinical manifestations such as high fever， chills， and alternating sensations of cold and heat are attributed to pathogenic heat constrained in the shaoyang. Meanwhile， soft tissue edema and serous cavity effusions are due to shaoyang dysfunction and internal water retention. In clinical practice， treating sepsis-related high fever requires addressing both the shaoyang-constrained heat and the associated edema and effusions. The therapeutic approach focuses on harmonizing the shaoyang and resolving internal fluids， using Chaihu Guizhi Ganjiang Decoction as the base formula with flexible modifications. Professor SHI emphasizes that this formula shows a rapid antipyretic effect， particularly in cases where multiple anti-infective treatments have failed.
