Long-Term Efficacy of Rehabilitation Following Arthroscopic Synovectomy in Patients With Rheumatoid Arthritis Treated With Biologic Agents.
10.5535/arm.2017.41.6.998
- Author:
Katsuaki KANBE
1
;
Chiaki SEKINE
Author Information
1. Department of Rehabilitation, Tokyo Women's Medical University, Medical Center East, Tokyo, Japan. kambe.katsuaki@twmu.ac.jp
- Publication Type:Original Article
- Keywords:
Rehabilitation;
Synovectomy;
Rheumatoid arthritis
- MeSH:
Arthritis, Rheumatoid*;
Biological Factors*;
C-Reactive Protein;
Humans;
Joints;
Rehabilitation*
- From:Annals of Rehabilitation Medicine
2017;41(6):998-1004
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To investigate the long-term efficacy of rehabilitation following arthroscopic synovectomy in patients with rheumatoid arthritis treated with biologic agents. METHODS: Arthroscopic synovectomy was performed in 29 joints of 17 patients, which were divided into two groups. Group 1 included arthroscopic synovectomy plus rehabilitation for 19 joints in 10 patients, and group 2 included arthroscopic synovectomy without rehabilitation for 10 joints in 7 patients. The Disease Activity Score C-reactive protein (DAS28-CRP), Health Assessment Questionnaire-Disability Index (HAQ-DI), and Functional Independence Measure (FIM) values (motor subscale) at 9.7 years after arthroscopic synovectomy were evaluated to identify the clinical factors related to outcomes. RESULTS: The increase in FIM score was significant in group 1 (p=0.05). HAQ-DI at 9 years was significantly decreased in group 1 (p=0.02). Therefore, arthroscopic synovectomy with rehabilitation was significant in improving FIM and HAQ-DI scores over a long period. Multiple regression analysis of FIM scores at 9 years indicated that rehabilitation (p=0.03) and disease duration (p=0.02) were significantly related to outcomes. FIM score at 9 years was significantly negatively correlated with disease duration (p=0.01, r=−0.58, Y=88.89–0.21X). CONCLUSION: Rehabilitation following arthroscopic synovectomy was effective in achieving high FIM scores over time in patients with rheumatoid arthritis.
