Research advances in the involvement of inflammatory response in cardioembolic stroke
10.19845/j.cnki.zfysjjbzz.2025.0145
- VernacularTitle:炎症反应参与心源性栓塞的研究进展
- Author:
Chen DU
1
,
2
;
Lijuan WANG
1
Author Information
1. 广东省人民医院神经内科，广东 广州 510030
2. 南方医科大学，广东 广州 510030
- Publication Type:Journal Article
- Keywords:
Cardioembolic stroke;
Inflammation;
Thrombosis;
Atrial fibrillation
- MeSH:
Inflammation
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(8):762-768
- CountryChina
- Language:Chinese
-
Abstract:
Cardioembolic stroke is a special type of ischemic stroke caused by cardiac diseases， and its development is closely associated with the structural and functional abnormalities of the heart. The pathophysiological mechanisms of this type of stroke are complex. It is often induced by thrombosis due to cardiac diseases， followed by thrombus detachment and entry into cerebral vessels， leading to ischemic injury and subsequent cascade reactions. Inflammatory response plays a crucial role in the development and progression of cardioembolic stroke， being involved in processes ranging from thrombosis to acute-phase brain injury after embolism， short-term neurological recovery， and long-term prognosis prediction， and can also be used as a biomarker and diagnostic factor. This article summarizes the mechanism by which inflammation contributes to the development and progression of cardioembolic stroke， as well as the current research advances in the etiology of cardioembolic stroke， the recovery of neurological function after stroke， and personalized treatment strategies.
- Full text:2025090415282678188炎症反应参与心源性栓塞的研究进展.pdf
