MOLECULAR TARGETS OF MORINGA OLEIFERA IN CANCERS (IN VITRO AND IN VIVO): A SYSTEMATIC REVIEW
https://doi.org/10.22452/jummec.sp2023no1.5
- Author:
Heba Akram Sharif Salhab
1
;
Al Shalabi Rolla Ziyad Mustafa
2
;
Julia Joseph
2
;
Nozlena Abdul Samad
2
Author Information
1. Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia.
2. Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Kepala Batas, Pulau Pinang, Malaysia
- Publication Type:Journal Article
- From:Journal of University of Malaya Medical Centre
2023;26(SPECIAL ISSUE 1):46-65
- CountryMalaysia
- Language:English
-
Abstract:
Cancer is unquestionably the greatest worldwide threat to humanity. With fewer side effects, natural
anticancer medicines are the most prevalent. Anticancer benefits of dietary polyphenols could be achieved
through carcinogen elimination, cancer cell signalling alteration, antioxidant enzymatic activities, and
apoptosis-inducing substances, according to the likely approach to anticancer effects of dietary polyphenols
research. This study aims to investigate the apoptosis induction mediated by Moringa oleifera in in vitro and
other molecular targets in vivo in all types of cancer studies, as well as to describe the most recent and
comprehensive research on antioxidant and anticancer characteristics. The terms "molecular target", "signalling
pathway", "apoptosis", "Moringa oleifera extract", "mechanism of action", "cancer", "tumour", "carcinoma",
and "melanoma" were used to search four online databases, PubMed, Scopus, ScienceDirect, and Google
Scholar, for relevant articles published between 2009 and 2019.
