THE EFFECT OF NIGHT-SHIFT WORK ON THE LEVEL OF URINARY 6-SULPHATOXYMELATONIN IN MEN OVER FIVE DAYS
- Author:
Yin Cheng Lim
1
;
Victor Chee Wai Hoe
1
;
Nirmala Bhoo Pathy
1
Author Information
- Publication Type:Journal Article
- Keywords: circadian rhythm; melatonin; shift work
- MeSH: Circadian Rhythm
- From:Journal of University of Malaya Medical Centre 2023;26(2):197-203
- CountryMalaysia
- Language:English
- Abstract: Night-shift work may adversely affect health. This study aimed to assess the effect of night-shift work on the level of urinary 6-sulphatoxymelatonin. Repeated measures of urinary 6-sulphatoxymelatonin on the morning before night-shift work and after first, third and fifth night-shift work was undertaken in 29 males, Malay, day-night-shift workers. A total of 29 male workers participated in this study. Median age was 29 years old. The highest level of urinary 6-sulphatoxymelatonin was at time point 1, followed by a significant reduction from time point 1 to time point 2. Subsequently, there was a progressive increase of urinary 6-sulphatoxymelatonin from time point 2 to 4. However, the urinary 6-sulphatoxymelatonin did not normalise at time point 4 and remained lower than the baseline
- Full text:2025082112262187370124389.pdf
