ULTRASOUND GUIDED FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) VERSUS FINE NEEDLE CAPILLARY SAMPLING (FNCS) OF THYROID NODULES
https://doi.org/10.22452/jummec.vol26no1.7
- Author:
Hooi Ching Koh
1
;
Sanjay Perapakaran
1
;
Hairulhasliza Harun
2
;
Syahrul Anuar Salleh
3
Author Information
1. Department of Radiology, Seberang Jaya Hospital, Jalan Tun Hussein Onn, 13700 Permatang Pauh, Pulau Pinang, Malaysia.
2. Department of Pathology, Seberang Jaya Hospital, Jalan Tun Hussein Onn, 13700 Permatang Pauh, Pulau Pinang, Malaysia.
3. Department of Surgery, Seberang Jaya Hospital, Jalan Tun Hussein Onn, 13700 Permatang Pauh, Pulau Pinang, Malaysia.
- Publication Type:Journal Article
- Keywords:
Fine Needle Aspiration Cytology (FNAC);
Fine Needle Capillary Sampling (FNCS);
Ultrasound Guided
- From:Journal of University of Malaya Medical Centre
2023;26(1):32-37
- CountryMalaysia
- Language:English
-
Abstract:
Introduction:Sampling of non-palpable thyroid nodule under ultrasound guidance has been widely used, however less studies done in comparing the efficacy of technique between fine needle aspiration cytology (FNAC) and fine needle capillary sampling (FNCS) under ultrasound guidance.
Objectives:This study aimed to determine the cytologic adequacy rates and sample quality obtained by both techniques under ultrasound guidance.
Methods:Ultrasound‐guided thyroid nodule samplings were performed on 88 patients, 44 of them had FNAC and another 44 FNCS technique. The slides obtained were scored using a predetermined scoring system comparing five parameters: background blood; amount of cellular material; appropriate architecture retention, degree of cellular degeneration and cellular trauma. The results were analysed using chi square and binary logistic regression test.
Results:Patient who underwent FNCS technique was 0.61times (95%CI) less likely to have large amount of background blood sample; 0.39times less likely to have sample with excellent architecture retention; 2.31times and 1.13times more likely to have sample with minimal cellular degeneration and minimal cellular trauma respectively when compare to FNAC. These were however not statistically significant. FNCS was 0.23times less likely to obtain sample with abundant cellular material compared to FNAC and it was statistically significant. Diagnostic adequacy rate was similar in both techniques and it was statistically significant.
Conclusions :Ultrasound‐guided FNAC and FNCS yielded comparable diagnostic adequacy rates. Our study did not prove a clear superiority of FNCS over FNAC or vice versa. Both techniques could be use in tandem to achieve better diagnostic accuracy.
- Full text:2025082010540239968107225.pdf
