RESPIRATORY FAILURE ASSOCIATED WITH DISTAL RENAL TUBULAR ACIDOSIS IN AN OLDER ADULT WITH SOUTHEAST ASIAN OVALOCYTOSIS AND CONCOMITANT THYROTOXIC ATRIAL FIBRILLATION
https://doi.org/10.22452/jummec.vol26no1.1
- Author:
Hoe Leong Sii
1
;
Sin Hui Ng
1
;
Kit Hou Chiang
1
;
Voon Fei Wong
1
Author Information
1. Department of Medicine, Hospital Sibu, KM 5 1/2, Jalan Ulu Oya, 96000 Sibu, Sarawak.
- Publication Type:Journal Article
- Keywords:
Distal Renal Tubular Acidosis;
Southeast Asian Ovalocytosis;
Respiratory Failure;
Nephrocalcinosis
- MeSH:
Acidosis, Renal Tubular
- From:Journal of University of Malaya Medical Centre
2023;26(1):1-4
- CountryMalaysia
- Language:English
-
Abstract:
Distal renal tubular acidosis (dRTA) is characterized by hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis and metabolic bone disease. It has been associated with Southeast Asian Ovalocytosis (SAO), particularly in malaria endemic region. We present a case of an older adult with dRTA who presented with respiratory failure as a result of hyperchloremic normal anion gap metabolic acidosis, in association with nephrocalcinosis and SAO, however, without hypokalaemia due to concurrent acute kidney injury. Oxygen therapy was able to be weaned off after treatment with alkali supplementation. Distal RTA may be associated with SAO, and early recognition and treatment of dRTA is paramount in preventing complications such as chronic kidney disease, metabolic bone disease and life-threatening respiratory arrest.
- Full text:2025082009552687235107119.pdf
