Modulation of Tooth Eruption – An Understanding at the Molecular and Biochemical Level
https://doi.org/10.56026/imu.19.1.54
- Author:
Sivakumar Arunachalam
1
;
Indumathi Sivakumar
2
;
Jitendra Sharan
3
;
Sabarinath Prasad
4
Author Information
1. School of Dentistry, IMU University, Malaysia
2. Faculty of Dentistry, SEGi University, Malaysia
3. Department of Dentistry, All India Institute of Medical Sciences, Bhuvaneswar, India
4. Department of Orthodontics, Hamdan Bin Mohammed College of Dental Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai 50505, United Arab Emirates
- Publication Type:Journal Article
- Keywords:
Tooth Eruption;
Dental Follicle;
Molecular Biology;
Eruption Mechanism
- MeSH:
Tooth Eruption;
Dental Sac;
Molecular Biology
- From:International e-Journal of Science, Medicine and Education
2025;19(1):54-62
- CountryMalaysia
- Language:English
-
Abstract:
Tooth eruption is a localised event whereby the signals for eruption for a given tooth are synthesised in the dental follicle of that tooth with a possible cross talk of signals coming from the adjacent stellate reticulum. The eruption process requires alveolar bone resorption that is primarily regulated by the dental follicle. This is reflected by the fact that failures of eruption often can be traced to either osteoclast deficiencies or to dental follicle abnormalities. Recent advances in application of molecular techniques to animal models allowed for better understanding of gene regulatory events involved in the physiology of tooth eruption. This article attempts to consolidate and organise the facts that offshoot from animal studies.
- Full text:20250815093217860836.-Sivakumar-Modulation-of-Tooth-Eruption-3.pdf
