A MIXED INFECTION OF INTESTINAL MICROSPORIDIOSIS AND SALMONELLOSIS IN A 2-YEAR-OLD BOY WITH INHERITED IMMUNODEFICIENCY SYNDROME

Author: Azlin Muhammad ^{1
,

2} ; Mekadina Bernadus ^{1
,

2} ; Rozliana Hanim Mat Hasan ³ ; Wathiqah Wahid ^{1
,

2}
Author Information

1. Department of Parasitology &
2. Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Wilayah Persekutuan Kuala Lumpur, Malaysia.
3. Bacterial section, Disease Division, National Public Health Laboratory, Sungai Buloh, Selangor, Malaysia.
Publication Type:Journal Article
Keywords: Intestinal Microsporidiosis; Hyper IgM Syndrome; Immunodeficiency
MeSH: Hyper-IgM Immunodeficiency Syndrome
From:Journal of University of Malaya Medical Centre 2021;24(2):27-30
CountryMalaysia
Language:English
Abstract: Gastrointestinal microsporidiosis is a major cause of chronic diarrhea in people with acquired immune deficienc syndrome. However, it can also affect individuals with inherited or congenital immunodeficiency. We reported a case of intestinal microsporidiosis and salmonellosis in a young boy with Hyper IgM syndrome. He presented with severe diarrhea and fever for 5 days. Stool examination showed heavy infection of Microsporidia spp. PCR confirmed the species as Enterocytozoon bieneusi. He was treated with albendazole for 25 days which abated the symptoms. To our knowledge, this is the first reported case of intestinal microsporidiosis in inherited immunodeficiency, X-linked Hyper IgM (XHIGM).
Full text:202508130936434178476093.pdf