Trial design of preventive treatment for episodic migraine in adults
10.19845/j.cnki.zfysjjbzz.2025.0118
- VernacularTitle:成人发作性偏头痛预防性治疗试验设计探讨
- Author:
Huanhuan FAN
1
;
Qiuyang HONG
1
;
Kegang CAO
2
Author Information
1. 北京中医医院顺义医院针灸科，北京 101300
2. 北京中医药大学中医脑病研究院，北京 100027
- Publication Type:Journal Article
- Keywords:
Migraine;
Preventive treatment;
Clinical trial;
Trial design
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(7):619-622
- CountryChina
- Language:Chinese
-
Abstract:
Migraine is a common chronic neurological disease，faces still certain limitations in the design of some clinical trials of migraine in China. Based on the principle of “PICO” in clinical research， this article summarizes the core contents of Guidelines for controlled trials of preventive treatment of episodic migraine in adults published by International Headache Society and its Clinical Trials Standing Committee， including subject selection， key points of trial design， and endpoint evaluation indicators. This article also discusses the deficiencies in current clinical trial design， so as to provide a basis for the design of clinical trials for migraine.
- Full text:2025081115210369186成人发作性偏头痛预防性治疗试验设计探讨.pdf
