Research progress on cross-protection of human papillomavirus vaccines
10.13200/j.cnki.cjb.004040
- VernacularTitle:人乳头瘤病毒疫苗交叉保护作用研究进展
- Author:
LIU Huan
- Publication Type:Journal Article
- Keywords:
Human papillomavirus(HPV);
Vaccine;
Cross-protection;
Immune protection
- From:
Chinese Journal of Biologicals
2025;38(08):998-1003+1011
- CountryChina
- Language:Chinese
-
Abstract:
Human papillomavirus(HPV)is one of the common sexually transmitted viruses in the human reproductive tract,which can cause cervical cancer, genital warts and other related diseases. HPV vaccines could not only prevent infection caused by the same HPV types as vaccines effectively, but also provide additional cross-protection against infection or diseases caused by non-vaccine types. This paper reviewed the cross-protection mechanisms of various types of HPV, the cross-protection effects of the commercial HPV vaccines, as well as the new preventive vaccines in progress, in order to provide a reference for the development of new generation of HPV preventive vaccines with broader protection