Functional recurrent abdominal pain in adults： A neglected manifestation of migraine
10.19845/j.cnki.zfysjjbzz.2025.0114
- VernacularTitle:成人功能性复发性腹痛：被忽视的偏头痛表现?
- Author:
Ke DING
1
;
Guodong XU
2
;
Hebo WANG
1
,
2
,
3
Author Information
1. 河北医科大学研究生院，河北 石家庄 050011
2. 河北省人民医院神经内科，河北 石家庄 050000
3. 河北省脑网络与认知障碍疾病重点实验室，河北 石家庄 050000
- Publication Type:Journal Article
- Keywords:
Functional recurrent abdominal pain;
Migraine;
Central sensitization;
Gut-brain axis
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(7):600-604
- CountryChina
- Language:Chinese
-
Abstract:
As the third-level diagnosis of migraine， recurrent gastrointestinal disturbance is a group of disorders with recurrent episodic attacks of abdominal pain and/or discomfort and nausea and/or vomiting that may be associated with migraine， and it is a clinical syndrome with the core symptom of abdominal pain， with the presence of clinical and neurobiological associations. This article reviews the similarities of the two diseases from the aspects of epidemiological characteristics， gender distribution tendency， clinical course， auxiliary examination， and treatment response， as well as three potential mechanisms in pathophysiology. This strong association between functional recurrent abdominal pain and migraine suggests that although there is no definitive evidence， adult functional recurrent abdominal pain， or at least its specific subsets， may belong to the spectrum of migraine. In other words， functional recurrent abdominal pain itself without headache may be a “migraine phenomenon”. In the future， it is necessary to conduct more rigorously designed observational studies on the association between the two diseases to clarify such possibility， in order to provide strong supporting evidence for the diagnosis and treatment of patients with functional recurrent abdominal pain and migraine and relieve pain as soon as possible.
- Full text:2025081113391632120成人功能性复发性腹痛：被忽视的偏头痛表现_.pdf
