Risk prediction and influencing factors of major adverse cardiovascular events in patients with acute myocardial infarction complicated with heart failure
10.3969/j.issn.1006-2483.2025.04.034
- VernacularTitle:急性心肌梗死合并心力衰竭患者主要不良心血管事件发生的影响因素及风险预测
- Author:
Qunmei WU
1
;
Hui ZHANG
1
;
Haomiao SUN
1
;
Chengsen ZHANG
1
Author Information
1. Health Management Center , Qingdao Central Hospital , University of Health and Rehabilitation Sciences , Qingdao , Shandong 266042 , China
- Publication Type:Journal Article
- Keywords:
Acute myocardial infarction;
Heart failure;
Major adverse cardiovascular events;
Risk factors;
Predictors
- From:
Journal of Public Health and Preventive Medicine
2025;36(4):149-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors and predictive risk of major adverse cardiovascular events (MACE) in patients with acute myocardial infarction (AMI) complicated with heart failure (HF). Methods A total of 380 AMI patients with HF in Qingdao Central Hospital, University of Health and Rehabilitation Sciences were enrolled from January 2022 to January 2024. All patients were followed up for 1 year after percutaneous coronary intervention (PCI) at admission. The occurrence of MACE during follow-up was recorded. The clinical data from the MACE group (n=64) and the no-MACE group (n=316) were collected and compared. Multivariate logistic regression analysis was utilized to analyze the influencing factors of the occurrence of MACE in patients with AMI complicated with HF. Results During 1-year follow-up, 64 cases had MACE among 380 patients, with an incidence rate of 16.84%. Multivariate logistic regression analysis indicated that LVEF, preoperative Killip grading and complete revascularization were risk factors of MACE occurrence in AMI patients with HF. The area under the curve of logistic regression model prediction was 0.841, indicating that the model had good predictive value. Conclusion The occurrence of MACE in AMI patients with HF after PCI is not optimistic, and the incidence rate of MACE is high. LVEF, preoperative Killip grading and complete revascularization are independent factors affecting the occurrence of MACE after surgery.
