Association of diabetes and risk of tuberculosis in community population in Shanghai
10.3969/j.issn.1006-2483.2025.04.009
- VernacularTitle:上海市社区人群糖尿病与结核病发病风险研究
- Author:
Jin LI
1
;
Qi ZHAO
2
;
Jinyan ZOU
1
;
Yong LI
1
;
Genming ZHAO
2
;
Yonggen JIANG
1
;
Liping LU
1
Author Information
1. Songjiang District Center for Disease Control and Prevention , Shanghai 201600 , China
2. Department of Epidemiology and Biostatistics , School of Public Health , Fudan University , Shanghai 200032 , China
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Tuberculosis;
Cohort study
- From:
Journal of Public Health and Preventive Medicine
2025;36(4):42-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the association of diabetes status with the development of tuberculosis (TB) among the community population in Shanghai, and to provide evidence for the formulation of tuberculosis prevention and control strategies. Methods This population-based cohort study was based on Shanghai Suburban Adult Cohort and Biobank (SSACB) in China. The baseline data were acquired by questionnaires, physical examinations and blood biochemistry tests. TB incidence was obtained by matching with TB management information system data. A Cox proportional risk model was established to assess the risk of tuberculosis. Results A total of 36 014 research subjects were included, with an average age of 56.3±11.3 years, of which 14 587 (40.5%) were male. Over 6 years of follow-up, 47 individuals progressed to tuberculosis (incidence rate: 19.8 per 100 000 person-year, 95% CI: 14.6 -26.4). An increased risk of TB was observed in participants with newly diagnosed diabetes compared with those without diabetes (adjusted hazard ratio [aHR], 2.73; 95% CI, 1.19 - 6.28). Conclusion The risk of tuberculosis in newly diagnosed diabetic patients is significantly increased, and strengthening tuberculosis screening for this population should be considered in practical work.
