Disease burden and annual change trends of gastric cancer in China in 1990 - 2021
10.3969/j.issn.1006-2483.2025.04.004
- VernacularTitle:1990—2021年中国胃癌疾病负担研究及年变化趋势分析
- Author:
Siming NING
1
,
2
,
3
;
Ruixia YANG
1
,
2
,
3
;
Yanan JIN
1
,
2
,
3
;
Yue YANG
1
,
2
,
3
;
Xiaoning KANG
4
,
5
Author Information
1. The Second Affiliated Hospital of Xi'
2. an Medical University , Xi'
3. an , Shanxi 710038, China
4. Xijing Hospital of Digestive Diseases , Air Force Medical University , Xi'
5. an , Shanxi 710032 , China
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Disease burden;
Incidence;
Prevalence;
Mortality;
Disability-adjusted life years
- From:
Journal of Public Health and Preventive Medicine
2025;36(4):17-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the burden and epidemic trends of gastric cancer in China from 1990 to 2021, and to provide a scientific basis for the formulation of effective prevention and control strategies. Methods Data from the 2021 Global Burden of Disease (GBD) database were used to extract the number of the incidence, prevalence, and death cases, as well as the disability-adjusted life years (DALY) for gastric cancer in China from 1990 to 2021. The corresponding crude rates and age-standardized rates were calculated. The Joinpoint regression model was employed to analyze the trends in the burden of gastric cancer, and a comprehensive examination was conducted from multiple dimensions including age, gender, and time. Results From 1990 to 2021, the age-standardized incidence rate (ASIR) of gastric cancer in China decreased from 48.03 per 100,000 to 29.05 per 100,000, the age-standardized prevalence rate (ASPR) decreased from 67.17 per 100,000 to 57.23 per 100,000, the age-standardized mortality rate (ASMR) decreased from 46.05 per 100,000 to 21.51 per 100,000, and the age-standardized DALY rate (ASDR) decreased from 1181.61 per 100,000 to 501.26 per 100,000. The AAPCs of ASIR, ASPR, ASMR, and ASDR were -1.61%, -0.50%, -2.44%, and -2.75%, respectively. The incidence, prevalence, mortality and DALY rates showed a trend of increasing first and then decreasing with age. Although females had higher incidence, prevalence, mortality, and DALY numbers in the older age groups, males exhibited higher crude rates across all age groups. Conclusion The overall disease burden of gastric cancer in China showed a downward trend from 1990 to 2021, and men and middle-aged and elderly people are the key populations for prevention and control efforts.
