Status and Progress of Research on Metabolomics of Cervical Cancer

Shaojun CHEN; Ling GAN; Xinkang CHEN; Lingling XIONG; Die LONG; Lulu CHEN; Mengzhuan WEI; Li HUA; Haixin HUANG

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Status and Progress of Research on Metabolomics of Cervical Cancer

VernacularTitle:宫颈癌代谢组学的研究现状与进展
Author: Shaojun CHEN ^{1
,

2} ; Ling GAN ³ ; Xinkang CHEN ³ ; Lingling XIONG ³ ; Die LONG ³ ; Lulu CHEN ³ ; Mengzhuan WEI ^{1
,

2} ; Li HUA ^{1
,

2} ; Haixin HUANG ^{1
,

2}
Author Information

1. Cancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, China
2. Engineering Technology Center of Liuzhou Gynecological Oncology Intelligent Guidance System, Liuzhou 545005, China.
3. Cancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, China.
Publication Type:REVIEWS
Keywords: Cervical cancer; Metabolomics; Diagnosis; Prediction; Prognosis
From: Cancer Research on Prevention and Treatment 2025;52(7):630-636
CountryChina
Language:Chinese
Abstract: Cervical cancer is one of the most common gynecological malignant tumors in China. Given their lack of obviously early symptoms, more than half of patients with cervical cancer are diagnosed in the middle and late stages of this malignancy, resulting in poor prognosis. Finding new therapeutic targets is the current research direction. Metabolomics, as a new omics technology, is expected to provide new targets for tumor precision diagnosis and treatment through the analysis of the changes and potential mechanisms of metabolites in tumor occurrence and development by chromatography, mass spectrometry, and other technologies. Herein, we review the research methods of metabolomics; metabolic characteristics of cervical cancer; and progress of the research on metabolomics in cervical cancer diagnosis, curative effect prediction, and prognosis evaluation to provide new ideas for the precise diagnosis and treatment of cervical cancer.