Efficacy of pudendal nerve modulation in the treatment of female pudendal neuralgia
10.3969/j.issn.1009-8291.2025.05.006
- VernacularTitle:阴部神经调控术治疗女性阴部神经痛的疗效观察
- Author:
Ziqin ZHOU
1
,
2
;
Xin SONG
3
;
Yinjun GU
4
;
Tingting LYU
3
;
Weilin FANG
3
;
Jin HUANG
3
;
Jianwei LYU
3
;
Zhikang CAI
3
;
Zhong WANG
3
Author Information
1. School of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai 200093
2. Department of Urology, Gongli Hospital, Shanghai 200135
3. Department of Urology, Gongli Hospital, Shanghai 200135
4. Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200001, China
- Publication Type:Journal Article
- Keywords:
pudendal nerve modulation;
sacral neuromodulation;
pudendal neuralgia;
3D printing;
female
- From:
Journal of Modern Urology
2025;30(5):395-399
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the clinical efficacy and safety of pudendal nerve modulation (PNM) in the treatment of female pudendal neuralgia (PN)，so as to promote the clinical application of this technique. Methods: A retrospective analysis was conducted on 20 female PN patients who failed conservative treatment at Gongli Hospital during Nov.2020 and Oct.2023.All patients underwent simultaneous PNM and sacral nerve modulation (SNM) with the assistance of 3D printing navigation.Dual-stage test electrodes for PNM and SNM were implanted，followed by alternate therapeutic trial for each modality.Secondary conversion rates and longitudinal outcomes，including visual analogue score (VAS)，patient health questionnaire-9 (PHQ-9)，and quality of life (QoL) scores were compared preoperatively，post-stage Ⅰ，and at 3，6，and 12 months post-stage Ⅱ. Results: All operations were successful.After the trial phase，the secondary conversion rate for PNM was significantly higher than that for SNM; 16 patients (16/20，80%) chose the second-phase PNM implantation surgery，3 (3/20，15%) chose second-phase SNM implantation，and 1 (1/20，5%) had electrodes removed due to ineffective results from both trials.Further assessment revealed that the improvements in VAS，PHQ-9，and QoL scores for PNM patients were significantly better than those for SNM patients after the first phase of surgery and at 3，6 and 12 months after the second-phase conversion (P<0.05).No complications such as electrode migration or infection were observed during the follow-up of 12-15 months. Conclusion: PNM provides more effective relief of pain symptoms and improvements in depressive states for female PN patients compared to SNM.With the assistance of 3D printing navigation，the operation is simple and safe，and offers stable therapeutic effects.It is worthy of clinical promotion and application.
