A comparison of the efficacy between single-position robot-assisted laparoscopic and retroperitoneal laparoscopic nephroureterectomy in the treatment of upper urinary tract urothelial carcinoma
10.3969/j.issn.1009-8291.2025.04.009
- VernacularTitle:一体位机器人辅助腹腔镜与后腹腔镜肾输尿管切除术治疗上尿路尿路上皮癌的疗效比较
- Author:
Wanrong XU
1
;
Tianyu GAO
1
;
Ziming KANG
1
;
Cheng WANG
1
;
Panfeng SHANG
1
Author Information
1. Department of Urology, The Second Hospital of Lanzhou University, Lanzhou 730030, China
- Publication Type:Journal Article
- Keywords:
upper tract urothelial carcinoma;
robot-assisted;
nephroureterectomy;
laparoscope;
single-position
- From:
Journal of Modern Urology
2025;30(4):315-321
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the clinical safety and efficacy of a single-position robot-assisted radical nephroureterectomy (RRUN) in the treatment of upper tract urothelial carcinoma (UTUC). Methods: A retrospective study was conducted on 136 UTUC patients who underwent RRUN (n=35) and laparoscopic radical nephroureterectomy (LRUN，n=101) in our hospital during Dec.2020 and Aug.2023.The perioperative and safety indicators of the two groups were compared.The intravesical recurrence-free survival (IVRFS)，recurrence-free survival (RFS)，and overall survival (OS) of the two groups were compared using Kaplan-Meier method. Results: There were no significant differences in the baseline data between the two groups (P>0.05).All surgeries were successfully completed without conversion to open surgery.RRUN demonstrated superior perioperative outcomes compared to LRUN in overall postoperative complication rate [37.1%(13/35) vs. 56.4%(57/101)]，postoperative hospital stay [6(5,7) days vs. 7(6,8) days]，and catheter indwelling time [3(2，4) days vs. 4(3，5) days]，with statistically significant differences (P<0.05).Safety indicators of both surgical approaches were similar (P>0.05).Survival analysis showed no significant difference in oncological outcomes between the two groups [IVRFS (1 year：92.1%，2 years：85.2%)，RFS (1 year:82.4%，2 years:74.9%)，OS (1 year:90.6%，2 years:84.2%)] (P>0.05). Conclusion: Compared with retroperitoneal LRUN，single-position RRUN for UTUC demonstrates comparable safety and oncological efficacy，while offering significant advantages in perioperative outcomes such as reducing postoperative complication rate and shortening hospital stay.
