Research progress on the relationship between vascular structure patterns and prognosis of renal cell carcinoma
10.3969/j.issn.1009-8291.2025.03.016
- VernacularTitle:血管结构模式与肾细胞癌预后关系的研究进展
- Author:
Dameng PAN
1
;
Qiming ZHANG
1
;
Min QIU
1
;
Lulin MA
1
Author Information
1. Department of Urology, Peking University Third Hospital, Beijing 100191, China
- Publication Type:Journal Article
- Keywords:
renal cell carcinoma;
vascular structure;
vascular maturity;
tumor grade;
prognosis
- From:
Journal of Modern Urology
2025;30(3):261-265
- CountryChina
- Language:Chinese
-
Abstract:
Vascular structure pattern，namely the maturity，morphology and distribution of blood vessels，as one of the pathological features of renal cell carcinoma (RCC)，cannot be ignored when the prognosis is concerned.The current mainstream classification of vascular structure patterns includes pseudoacini，Golgi，lacunar and dispersion patterns.Many studies have shown that the vascular structure patterns in RCC are closely related to the diagnosis and prognosis.Early features such as dendritic penetration of the endothelium contribute to the differential diagnosis of RCC，while different vascular structure patterns are not only related to tumor grade，but also affect the responsiveness of targeted therapy and prognosis.Evaluating these vascular structural patterns can help to understand the biological behaviors of tumors and guide the treatment options，but a unified assessment of vascular structural patterns is still lacking.This paper reviews the research progress on the relationship between vascular structure patterns and RCC prognosis，aiming to provide clinical reference.
