Efficacy of laparoscopic radical cystectomy with indocyanine green fluorescence imaging versus standard lymph node dissection: a randomized comparative study
10.3969/j.issn.1009-8291.2025.03.006
- VernacularTitle:腹腔镜膀胱癌根治术中采用吲哚菁绿荧光显像与标准淋巴结清扫临床疗效的随机对比研究
- Author:
Lifeng LIU
1
;
Na CAO
2
;
Yansong GUO
1
;
Hao WANG
1
;
Xiaopeng WANG
1
;
Fengshuo YANG
1
;
Yuepeng HU
1
;
Longjiang TIAN
1
;
Dawei TIAN
3
Author Information
1. Department of Urology, Cangzhou People's Hospital, Cangzhou 061000
2. Department of Nursing, Cangzhou Medical College, Cangzhou 061000
3. Department of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China
- Publication Type:Journal Article
- Keywords:
muscle invasive bladder cancer;
fluorescence imaging;
indocyanine green;
pelvic lymph node dissection;
radical cystectomy
- From:
Journal of Modern Urology
2025;30(3):212-214
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the efficacy，safety and feasibility of regional lymph node dissection in laparoscopic radical surgery for bladder cancer under the guidance of indocyanine green fluorescence imaging. Methods: A total of 30 patients with muscle invasive bladder cancer (T2/T3NxM0) who volunteered to enter the clinical trial were randomly divided into the indocyanine green imaging guided laparoscopic regional lymph node dissection group (n=15) and the standard pelvic lymph node dissection group (n=15).The number of positive lymph nodes，operation time，intraoperative bleeding volume，incidence of lymph leakage，and tumor recurrence and metastasis rate 2-year after surgery were collected. Results: The number of positive lymph nodes was (4.20±1.66) and (4.60±1.72) respectively in the indocyanine green and standard groups，with no statistically significant difference (P>0.05).There were no statistically significant difference in the tumor recurrence and metastasis rates 2-year after surgery between the two groups (P>0.05).However，the indocyanine green group had shorter operation time，less intraoperative bleeding volume，and lower incidence of lymphatic leakage than the standard group (P<0.05). Conclusion: Indocyanine green fluorescence imaging guided laparoscopic lymph node dissection has comparable clinical efficacy to standard lymph node dissection，but with fewer complications.
