Acute acro-paraesthesia and bilateral clumsy hand syndrome rare presenting manifestation of vitamin B12 deficiency: a case report highlighting clinicoradiological findings at diagnosis and follow-up
- Author:
Sumit.Kumar Sonu
1
;
Yogesh Lalmalani
1
;
Sumeet Kumar
2
;
Kamal Verma
1
Author Information
- Publication Type:Case Reports
- From:Neurology Asia 2020;25(4):627-630
- CountryMalaysia
- Language:English
- Abstract: Subacute combined degeneration of the spinal cord (SCD) is a neurodegenerative disease characterized by subacute progression in the central and peripheral nervous systems mainly caused by vitamin B12 deficiency.1 In the diagnosis of vitamin B12 deficiency, measurement of urine methylmalonic acid (MMA) and serum homocysteine levels has been reported as more useful than measurement of total vitamin B12 level.2 We report a rare case of SCD that we diagnosed by determining urine MMA, serum homocysteine levels with significant neurologic symptoms and characteristic magnetic resonance imaging (MRI) findings of the spinal cord, in the absence of characteristic findings of vitamin B12 deficiency and anaemia. Informed written consent obtained and documented.
- Full text:20250724102331106557.2020my0092.pdf
