Association between beat-to-beat blood pressure variability and prognosis in patients with acute ischemic stroke undergoing mechanical thrombectomy
10.19845/j.cnki.zfysjjbzz.2025.0103
- VernacularTitle:急性缺血性卒中机械取栓患者心动周期间血压变异性与预后的相关性研究
- Author:
Tao HAO
1
;
Siji WANG
2
Author Information
1. 陕西省宝鸡高新医院神经内科，陕西 宝鸡 721013
2. 吉林大学第一医院卒中中心，吉林 长春 130021
- Publication Type:Journal Article
- Keywords:
Acute ischemic stroke;
Mechanical thrombectomy;
Beat-to-beat blood pressure variability;
Prognosis;
Association
- MeSH:
Prognosis
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(6):545-549
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between beat-to-beat blood pressure variability（BPV）and prognosis in patients with acute ischemic stroke（AIS）undergoing mechanical thrombectomy（MT）. Methods A retrospective study was conducted among 52 AIS patients who underwent MT in Stroke Center of The First Hospital of Jilin University，and beat-to-beat BPV was monitored during hospitalization. The patients were followed up to observe modified Rankin Scale（mRS）score on day 90 after disease onset，and the patients were divided into good prognosis group（mRS≤1）and poor prognosis group（mRS>1）. The two groups were compared in terms of beat-to-beat BPV during hospitalization. A multivariate logistic regression analysis was used to investigate the association between beat-to-beat BPV and prognosis. Results Compared with the good prognosis group，the poor prognosis group had significantly higher beat-to-beat successive variation（SV）and average real variability（ARV）of systolic blood pressure（SBP）[SBP-SV： 2.63（1.84，3.48）vs 3.28（2.87，4.08），P=0.032； SBP-ARV： 2.06（1.30，2.55）vs 2.59（2.23，3.53），P=0.006]. After adjustment for confounding factors such as age，sex，risk factors for stroke，and baseline NIHSS score，the multivariate logistic regression analysis showed that beat-to-beat SBP-SV（OR=2.760，95%CI 1.168-6.522，P=0.021）and SBP-ARV（OR=3.916，95%CI 1.278-12.002，P=0.017）were associated with the poor prognosis of patients. Conclusion Beat-to-beat BPV is independently associated with 90-day poor prognosis in AIS patients undergoing MT，and therefore，it can be used as a predictive factor for prognosis.
- Full text:2025071714044181616急性缺血性卒中血管内治疗临床预后因素研究进展.pdf
