Research advances in the application of liquid biopsy in the diagnosis and treatment of hepatocellular carcinoma
- VernacularTitle:液体活检在肝细胞癌诊断及治疗中的应用
- Author:
Yulong LI
1
;
Xinxin ZHANG
1
Author Information
- Publication Type:Review
- Keywords: Hepatocellular Carcinoma; Liquid Biopsy; Neoplastic Cells， Circulating; Circulating Tumor DNA; Extracellular Vesicles
- From: Journal of Clinical Hepatology 2025;41(6):1194-1198
- CountryChina
- Language:Chinese
- Abstract: Hepatocellular carcinoma is one of the most common cancers， and due to the lack of obvious specific symptoms in its early stage， patients are often in the advanced stage at the time of diagnosis and tend to have a poor prognosis. Timely diagnosis and effective treatment in the early stage can help to prolong the survival time of patients. Liquid biopsy is a noninvasive technique that can obtain the information of tumor by detecting and analyzing related biomarkers， including circulating tumor cells， circulating tumor DNA， and extracellular vesicles， thereby contributing to early diagnosis， molecular pathological typing， and prognosis prediction. This article reviews the research advances in the application of liquid biopsy in the diagnosis and treatment of hepatocellular carcinoma.
