Research advances in sporadic late-onset nemaline myopathy
10.19845/j.cnki.zfysjjbzz.2025.0078
- VernacularTitle:散发性成人杆状体肌病的研究进展
- Author:
Bing ZHAO
1
;
Chuanzhu YAN
1
,
2
Author Information
1. 山东大学齐鲁医院（青岛）神经内科，山东 青岛 266035
2. 山东省罕见病线粒体医学重点实验室，山东 济南 250012
- Publication Type:Journal Article
- Keywords:
Sporadic late-onset nemaline myopathy;
Muscle pathology;
M protein;
Autologous stem cell transplantation;
Immunotherapy
- MeSH:
Immunotherapy
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(5):409-413
- CountryChina
- Language:Chinese
-
Abstract:
Sporadic late-onset nemaline myopathy （SLONM） is a rare， acquired， and treatable myopathy with a subacute or chronic progressive clinical course， characterized by asymmetric muscle atrophy and weakness in the axial and limb muscles， with or without involvement of respiratory and cardiac muscles. The only definitive diagnostic method at present is the identification of rods accumulation in muscle fibers by muscle biopsy pathology. This article provides a review of the clinical manifestations， diagnostic evaluations， muscle pathology， and advances in the treatment of SLONM.
- Full text:2025071616014978017散发性成人杆状体肌病的研究进展.pdf
