Clinical manifestations and prognosis of patients with hemichorea-hemiballism： An analysis of 25 cases
10.19845/j.cnki.zfysjjbzz.2025.0062
- VernacularTitle:25例偏侧舞蹈症患者的临床表现与预后分析
- Author:
Beiqing SU
1
;
Wenbin HU
2
Author Information
1. 安徽中医药大学，安徽 合肥 230012
2. 安徽中医药大学神经病学研究所附属医院，安徽 合肥 230061
- Publication Type:Journal Article
- Keywords:
Hemichorea-hemiballism;
Clinical analysis;
Acute cerebrovascular disease;
Hyperglycemia;
Cranial imaging
- MeSH:
Hyperglycemia
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(4):310-315
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the cause，pathogenesis，clinical manifestations，treatment，and prognosis of secondary hemichorea based on related clinical features and examinations by summarizing the medical records of 25 patients with secondary hemichorea-hemiballism. Methods An analysis was performed for 25 patients with hemichorea-hemiballism who were admitted and treated from July 2018 to April 2024，including general status，clinical features，laboratory examinations，MRI or CT examination，treatment methods，and prognosis. Results Of all 25 patients，11 （44.0%） had acute cerebrovascular diseases [including 7 cases （28.0%） of cerebral infarction，3 cases （12.0%） of cerebral hemorrhage，and 1 case （4.0%） of moyamoya disease]，13 （44.0%） had hyperglycemia，and 1 had unknown causes. Of all 25 patients with hemichorea-hemiballism after treatment of the primary disease and symptomatic treatment，18 patients had significant improvements in hemichorea symptoms，and 7 had disappearance of hemichorea symptoms. One patient experienced recurrence after half a year due to self-withdrawal of medication，and the other patients took medication regularly，with no recurrence at follow-up half a year later.Conclusion Hemichorea-hemiballism is more common in the elderly，and acute cerebrovascular disease is the most common cause of hemichorea-hemiballism，followed by hyperglycemia，with the basal ganglia as the main lesion site. In addition to the treatment of the primary disease，symptomatic treatment with haloperidol，clonazepam，or risperidone can significantly improve clinical symptoms and help to achieve a good prognosis.
- Full text:20250716134930365425例偏侧舞蹈症患者的临床表现与预后分析.pdf
