Features of non-motor symptoms and substantia nigra ultrasound in essential tremor
10.19845/j.cnki.zfysjjbzz.2025.0061
- VernacularTitle:特发性震颤的非运动症状及黑质超声的相关研究
- Author:
Xuejiao CHEN
1
;
Lei CHEN
2
Author Information
1. 山西省煤炭中心医院，山西 太原 030006
2. 天津市环湖医院，天津 300350
- Publication Type:Journal Article
- Keywords:
Essential tremor;
Non-motor symptom;
Transcranial substantia nigra sonography
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(4):306-309
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the features of non-motor symptoms and transcranial substantia nigra ultrasound in essential tremor （ET）. Methods General data were collected from 50 patients with ET and 50 healthy controls，and non-motor symptom scales and transcranial nigra sonography （TCS） were used for assessment. The t-test，the non-parametric test，and the chi-square test were used for comparison of general data，scale assessment results，and TCS findings between the two groups. Results There were significant differences between the ET group and the healthy control group in the total scores of NMSS，MoCA，HAMA，HAMD，PSQI，ESS，and FSS and the incidence rates of cognitive impairment，moderate or severe anxiety，poor sleep，and daytime sleepiness，while there were no significant differences in the incidence rates of moderate or severe depression and fatigue between the two groups. There were no significant differences between the two groups in terms of “hyperechoic area of the left side” “hyperechoic area of the right side” “hyperechoic area of both sides” “S/M value” “the number of cases with a hyperechoic area of >0.2 cm2 for at least one side” “the number of cases with an S/M ratio of >7%” and “the number of cases with positive TCS results”. Conclusion Compared with healthy controls，ET patients are more susceptible to cognitive impairment，anxiety，depression，poor sleep quality，daytime sleepiness，and fatigue，and the non-motor symptoms of ET should be taken seriously in clinical practice. TCS examination has a relatively low diagnostic value in ET patients and healthy individuals.
- Full text:2025071613374086340特发性震颤的非运动症状及黑质超声的相关研究.pdf
