Research advances in MEF2D in neurological disorders
10.19845/j.cnki.zfysjjbzz.2025.0056
- VernacularTitle:MEF2D在神经系统疾病中的研究进展
- Author:
Tengfei JIAO
1
;
Abudusalamu RENA
1
;
Dengfeng HAN
1
Author Information
1. Department of Neurology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
- Publication Type:Journal Article
- Keywords:
MEF2D;
Neurological disorders;
Research advances
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(3):279-283
- CountryChina
- Language:Chinese
-
Abstract:
Neurological disorders are an important cause of global human disease burden, but the mechanisms of the development and progression of neurological disorders remain unclear, and most studies have shown that they are associated with the expression of mutations in human genes. MEF2D, as an important transcription factor in the MEF2 family, plays an important role in both physiological and pathological processes. Related studies have found that MEF2D can be involved in neuronal survival, regulate neuronal responses to stimuli, and participate in the pathogenic process of neurological disorders. This article reviews the research advances in MEF2D in common neurological disorders.
- Full text:2025071611045380260MEF2D在神经系统疾病中的研究进展.pdf