Advances in proteomic research on cognitive disorder
10.19845/j.cnki.zfysjjbzz.2025.0054
- VernacularTitle:认知障碍的蛋白组学研究进展
- Author:
Jiangyan PEI
1
,
2
;
Weizhong JI
2
Author Information
1. 青海大学研究生院，青海 西宁 810016
2. 青海省人民医院，青海 西宁 810007
- Publication Type:Journal Article
- Keywords:
Cognitive disorder;
Proteomics technology;
Biomarkers
- MeSH:
Biomarkers
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(3):267-272
- CountryChina
- Language:Chinese
-
Abstract:
Cognition is the intelligent processing of the brain， which affects the acquisition and realization of knowledge in the body， including learning， memory， thinking， language， emotion， spirit， and other psychological and social activities. Cognitive impairment refers to abnormalities in the processing of higher-order intellectual activities in the brain， such as learning， memory， thinking， and judgment， which leads to severe learning and memory difficulties， and it is often accompanied by pathological developments including aphasia and apraxia， which is mainly caused by Alzheimer disease， cerebrovascular diseases， and traumatic brain injury. At present， the etiology of cognitive impairment remains unclear. Nowadays， with the continuous development of modern science and technology， proteomics technology has been widely used in the field of clinical medical research and can provide a scientific basis for the diagnosis and treatment of diseases and the development of new drugs. This article reviews the research advances in proteomics technologies， humoral proteomics of cognitive disorders， brain tissue proteomics， and proteomics research in cognitive disorders at high altitude， in order to further reveal the application and development of proteomics in cognitive disorders.
- Full text:2025071610445522086认知障碍的蛋白组学研究进展.pdf
