Mechanisms of Parkinson disease with peripheral neuropathy
10.19845/j.cnki.zfysjjbzz.2025.0026
- VernacularTitle:帕金森病伴周围神经病变的机制
- Author:
Houwen ZHANG
1
;
You WU
1
,
2
Author Information
1. 浙江中医药大学第二临床医学院，浙江 杭州 310053
2. 浙江中医药大学附属第二医院神经内科，浙江 杭州 310005
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Peripheral neuropathy;
Mechanism
- MeSH:
Parkinson Disease
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(2):133-136
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson disease （PD） is the second most prevalent neurodegenerative disorder and predominantly impacts the extrapyramidal system. This condition arises from the degeneration of the dopaminergic nigrostriatal pathway. In recent years， studies have shown that PD pathology and lesions are not limited to the center nervous system， and that PD is a systemic and multisystem disease. The concurrence of PD with peripheral neuropathy （PN） has been increasingly acknowledged， although its pathogenesis remains elusive. The motor symptoms in PD patients often mask the symptoms of PN， leading to relatively low clinical recognition of PD coexisting with PN. This poses challenges in the clinical diagnosis and treatment of PD. This review comprehensively summarize the pathogenesis of PD coexisting with PN.
- Full text:2025071514281603279帕金森病伴周围神经病变的机制.pdf
